期刊论文、会议论文

Li, Shuaicheng

英文

BMC Bioinformatics

1471-2105

2018

19

19

13-24

29th Internatioinal Conference on Genome Informatics (GIW) - Bioinformatics

DEC 03-05, 2018

Yunnan, PEOPLES R CHINA

[Xiao, Zhoujian;Yu, Runsheng] South China Normal Univ, HEMC Guangzhou Higher Educ Mega Ctr Campus, Guangzhou, Guangdong, Peoples R China.^[Wang, Ziwei] Hunan Agr Univ, Nongda Rd, Changsha, Hunan, Peoples R China.^[Chen, Yin;Jiang, Xiaosen] Huazhong Univ Sci & Technol, Luoyu Rd 1037, Wuhan, Hubei, Peoples R China.^[Zhang, Yuwei;Li, Shuaicheng] City Univ Hong Kong, Kowloon, 83 Tat Chee Ave, Hong Kong, Peoples R China.

CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND

BMC

10.1186/s12859-018-2517-3

Publication costs are funded by the GRF Research Projects 9042348 (CityU 11257316). The work described in this paper was also supported by the project.

本校为其他机构

Background: Finding peptides with high binding affinity to Class I major histocompatibility complex (MHC-I) attracts intensive research, and it serves a crucial part of developing a better vaccine for precision medicine. Traditional methods cost highly for designing such peptides. The advancement of computational approaches reduces the cost of new drug discovery dramatically. Compared with flourishing computational drug discovery area, the immunology area lacks tools focused on in silico design for the peptides with high binding affinity. Attri...