期刊论文

英文

Oxidative Medicine and Cellular Longevity

1942-0900

2021

2021

10.1155/2021/8850112

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31871804]; Natural Science Foundation of Hunan Province, ChinaNatural Science Foundation of Hunan Province [2019JJ40272, 2020JJ4036]; Scientific Research Foundation of Shaoyang College, China [2020HX122]

本校为第一机构

The maintenance of homeostasis is essential for mitigating stress and delaying degenerative diseases such as Alzheimer's disease (AD). AD is generally defined as the abnormal production of beta-amyloid (A beta) and advanced glycation end products (AGEs). The effects of l-theanine on A beta and AGE generation were investigated in this study. Decreased AGEs and A beta(1-42) levels were reflected by increased acetylcholine (ACh) concentration and acetylcholinesterase (AChE) activity inhibition compared to model rats. l-Theanine also inhibited nuclear factor-kappa B (p65) protein expression by act...