With molecular biology research coming into the post-genome era focusing on proteomics, protein-protein interaction (PPI) has become an important topic of proteomics. The computational methods are widely used to analyze PPI data and guide experimental design for biologists, because they only need lower cost and have a shorter experimental period. In two aspects of constructing PPI network and analyzing it, all kinds of computational methods are surveyed. When it comes to constructing PPI network, some technologies, which use machine learning methods, are introduced, such as predicting PPI from...