期刊论文

Advances in the study of the proteome of Fasciola

中文

中国病原生物学杂志

1673-5234

2020

15

8

987-990

10.13350/j.cjpb.200825

本校为第一机构

寄生在肝脏胆管内的人兽共患的片形吸虫病,对动物和人体的肝脏造成损害,致生长迟缓、动物死亡、牲畜产量下降。蛋白质组学数据的发展帮助我们了解片形吸虫生物学、片形吸虫病诊断及免疫作用重要因子,为片形吸虫病的防制打下了良好的基础。本文综述了片形吸虫排泄分泌蛋白组、体被蛋白组、细胞外囊泡蛋白组研究进展。

Fasciolosis is a parasitic zoonosis in the liver bile ducts caused by Fasciola hepatica and F.gigantica.The disease causes damage to the liver of animals and humans,retarded growth,a large number of deaths in animals,and a decrease in livestock production.Recent research on proteomics is helping us to understand the biology of F.hepatica and F.gigantica,to diagnose fasciolosis,and to understand key aspects of its immunological effects,thus providinge a good basis for the prevention and control of fasciolosis.This paper reviews the excretory secretory proteome,tegument prote...