Use of Chlorogenic Acid against Diabetes Mellitus and Its Complications

成果类型：

期刊论文

作者：

Yan, Yongwang;Zhou, Xu;Guo, Kangxiao;Zhou, Feng;Yang, Hongqi*

通讯作者：

Yang, Hongqi

作者机构：

[Yang, Hongqi; Yan, Yongwang] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha, Peoples R China.

[Zhou, Feng; Guo, Kangxiao; Yan, Yongwang] Changsha Hlth Vocat Coll, Pharmaceut Coll, Changsha, Peoples R China.

[Zhou, Xu] Changsha Hosp Tradit Chinese Med, Dept Gastroenterol, Changsha, Peoples R China.

通讯机构：

[Yang, Hongqi] H

Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha, Peoples R China.

语种：

英文

关键词：

chlorogenic acid;glucose;lipid;antidiabetic agent;antioxidant;chlorogenic acid;glucose;insulin;clinical trial (topic);diabetes mellitus;diabetic complication;diabetic nephropathy;diabetic neuropathy;diabetic retinopathy;drug effect;drug use;enzyme activity;glucose metabolism;human;inflammation;insulin release;insulin resistance;lipid metabolism;nonhuman;oxidative stress;primary prevention;randomized controlled trial (topic);Review;signal transduction;animal;biosynthesis;diabetes mellitus;diabetic complication;gene expression regulation;metabolism;Animals;Antioxidants;Chlorogenic Acid;Diabetes Complications;Diabetes Mellitus;Gene Expression Regulation, Enzymologic;Glucose;Humans;Hypoglycemic Agents;Insulin;Insulin Resistance;Lipid Metabolism;Metabolic Networks and Pathways;Oxidative Stress

期刊：

Journal of Immunology Research

ISSN：

2314-8861

年：

2020

卷：

2020

页码：

1-6

DOI：

10.1155/2020/9680508

基金类别：

Chlorogenic acid (CA) is a phenolic compound commonly found in human plant-based diets. CA is the main component of many traditional Chinese medicine preparations, and in recent years, it has been found to have hypoglycemic, hypolipidemic, anti-inflammatory, antioxidant, and other pharmacological properties. Specifically, CA relieves the effects of, and prevents, diabetes mellitus (DM). In addition, CA is also beneficial against complications arising from DM, such as diabetic nephropathy (DN), diabetic retinopathy (DR), and diabetic peripheral neuropathy (DPN). Herein, we review the use of CA in the prevention and treatment of DM and its complications, providing a background for further research and medical uses. Scientific Research Fund of the Hunan Provincial health and planning Business Committee C2017010 Education Department of Hunan Province 17C0123

机构署名：

本校为第一且通讯机构

院系归属：

生物科学技术学院

摘要：

Chlorogenic acid (CA) is a phenolic compound commonly found in human plant-based diets. CA is the main component of many traditional Chinese medicine preparations, and in recent years, it has been found to have hypoglycemic, hypolipidemic, anti-inflammatory, antioxidant, and other pharmacological properties. Specifically, CA relieves the effects of, and prevents, diabetes mellitus (DM). In addition, CA is also beneficial against complications arising from DM, such as diabetic nephropathy (DN), diabetic retinopathy (DR), and diabetic peripheral ...

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