Long-term consumption of cadmium (Cd)rice will cause a series of diseases and adversely affect the human health system. It is of great significance to ensure a safe Cd content in rice for food security. In this article, three Cd accumulation processes were systematically summarized: absorption of Cd by the rice roots, the transport from the roots to the shoots and to the grains. The physiological mechanisms involved in these three important processes were reviewed from the physiological perspective and the molecular regulatory mechanisms of related genes were summarized from the perspective of...