Persistent Ventral Anterior Cingulate Cortex and Resolved Amygdala Hyper-responses to Negative Outcomes After Depression Remission: A Combined Cross-sectional and Longitudinal Study

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成果类型：

期刊论文

作者：

Zhang, Xiaocui;Wang, Xiang;Dong, Daifeng;Sun, Xiaoqiang;Zhong, Xue;...

作者机构：

[Zhang, Xiaocui; Xiong, Ge; Yao, Shuqiao; Cheng, Chang; Sun, Xiaoqiang; Wang, Xiang; Zhong, Xue; Dong, Daifeng] Cent South Univ, Xiangya Hosp 2, Med Psychol Ctr, Changsha, Peoples R China.

[Zhang, Xiaocui; Xiong, Ge; Yao, Shuqiao; Cheng, Chang; Sun, Xiaoqiang; Wang, Xiang; Zhong, Xue; Dong, Daifeng] Cent South Univ, Med Psychol Inst, Changsha, Peoples R China.

[Zhang, Xiaocui; Yao, Shuqiao; Wang, Xiang] Natl Clin Res Ctr Mental Disorders, Changsha, Peoples R China.

[Rao, Hengyi; Chai, Ya] Shanghai Int Studies Univ, Key Lab Appl Brain & Cognit Sci, Shanghai, Peoples R China.

[Lei, Hui] Hunan Agr Univ, Coll Educ, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

Amygdala;Depression;Negative outcome;Risky decision making;Ventral anterior cingulate cortex

期刊：

Biological Psychiatry

ISSN：

0006-3223

年：

2023

卷：

期：

页码：

268-278

DOI：

10.1016/j.biopsych.2022.09.003

基金类别：

National Natural Science Foundation of China; Natural Science Foundation of Hunan, China; [81501178]; [31671144]; [82071532]; [2017JJ3454]

机构署名：

本校为其他机构

院系归属：

教育学院

摘要：

BACKGROUND: Major depressive disorder (MDD) is a highly prevalent mood disorder affecting more than 300 million people worldwide. Biased processing of negative information and neural hyper-responses to negative events are hallmarks of depression. This study combined cross-sectional and longitudinal experiments to explore both persistent and resolved neural hyper-responses to negative outcomes from risky decision making in patients with current MDD (cMDD) and remitted MDD (rMDD). METHODS: A total of 264 subjects participated in the cross-section...

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Persistent Ventral Anterior Cingulate Cortex and Resolved Amygdala Hyper-responses to Negative Outcomes After Depression Remission: A Combined Cross-sectional and Longitudinal Study

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