Aberrant dynamics of the default mode network activity in patients with obsessive-compulsive disorder

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成果类型：

期刊论文

作者：

Cui, Yan;Lei, Hui;Yu, Shuang;Chen, Ke;Xia, Yang;...

通讯作者：

Guo, Daqing;Yao, DZ;Zhu, XZ

作者机构：

[Guo, Daqing; Xia, Yang; Yao, Dezhong; Yu, Shuang; Cui, Yan; Xu, Ruxiang; Chen, Ke] Univ Elect Sci & Technol China, MOE Key Lab NeuroInformat, Sichuan Acad Med Sci, Dept Neurosurg,Sichuan Prov Key Lab Human Dis Gene, Chengdu, Peoples R China.

[Guo, Daqing; Xia, Yang; Yao, Dezhong; Yu, Shuang; Cui, Yan; Xu, Ruxiang; Chen, Ke] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Chengdu, Peoples R China.

[Guo, Daqing; Xia, Yang; Yao, Dezhong; Yu, Shuang; Cui, Yan; Chen, Ke] Univ Elect Sci & Technol China, Sch Life Sci & Technol, Chengdu Brain Sci Inst, Clin Hosp,Ctr Informat Med, Chengdu 611731, Peoples R China.

[Lei, Hui] Hunan Agr Univ, Coll Educ, Changsha, Peoples R China.

[Zhu, Xiongzhao; Lei, Hui] Cent South Univ, Xiangya Hosp 2, Med Psychol Ctr, Changsha, Hunan, Peoples R China.

通讯机构：

[Guo, DQ; Yao, DZ ] U

[Zhu, XZ ] C

Univ Elect Sci & Technol China, MOE Key Lab NeuroInformat, Sichuan Acad Med Sci, Dept Neurosurg,Sichuan Prov Key Lab Human Dis Gene, Chengdu, Peoples R China.

Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Chengdu, Peoples R China.

Univ Elect Sci & Technol China, Sch Life Sci & Technol, Chengdu Brain Sci Inst, Clin Hosp,Ctr Informat Med, Chengdu 611731, Peoples R China.

语种：

英文

关键词：

Obsessive-compulsive disorder;Default mode network;Coactive micropatterns;Brain dynamics

期刊：

Cognitive Neurodynamics

ISSN：

1871-4080

年：

2025

卷：

期：

页码：

1-16

DOI：

10.1007/s11571-025-10288-0

基金类别：

the STI 2030-Major Projects [2022ZD0208500]; STI [2023NSFSC1595]; Sichuan Science and Technology Program [2022QN15]; Hospital Fund of Sichuan Provincial People's Hospital

机构署名：

本校为其他机构

院系归属：

教育学院

摘要：

Obsessive compulsive disorder (OCD) is a serious mental disease highly associated with the dysfunctional dynamics of brain networks. The default mode network (DMN) is an essential brain network responding to various cognitive functions, which has been reported the abnormality in OCD patients. However, the underlying evolutions of temporal-spatial neurodynamics in fast-changing DMN activity of OCD remains largely unclear. In the present work, we tried to address this issue by tracking the neurodynamic structure of electrophysiological DMN activity in OCD patients during the resting state. To ac...

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Aberrant dynamics of the default mode network activity in patients with obsessive-compulsive disorder

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