Genetic engineering strategies for construction of multivalent chimeric VLPs vaccines

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Lei, Xinnuo;Cai, Xiong;Yang, Yi

通讯作者：

Lei, XN

作者机构：

[Lei, Xinnuo; Yang, Yi] Hunan Agr Univ, RCRV, Prov Key Lab Prot Engn Anim Vaccines, Changsha, Hunan, Peoples R China.

[Lei, Xinnuo; Yang, Yi] Hunan Agr Univ, Coll Vet Med, LFP, Changsha, Hunan, Peoples R China.

[Cai, Xiong] Hunan Univ Chinese Med, Inst Innovat & Appl Res Chinese Med, Changsha, Hunan, Peoples R China.

[Lei, Xinnuo] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Lei, XN ] H

Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

语种：

英文

关键词：

Chimeric virus-like particles;VLPs vaccine;capsid;construction strategy;envelope;foreign antigens;genetic fusion;multivalent vaccines

期刊：

Expert Review of Vaccines

ISSN：

1476-0584

年：

2020

卷：

期：

页码：

235-246

DOI：

10.1080/14760584.2020.1738227

基金类别：

This paper was funded by grants from the Hunan Provincial Natural Science Foundation (grant no. 2018JJ2293 to CX), Hunan Education Department’s Science & Research Project (grant no. 17K069). We would like to thank Xiuyue Chen, Yifan Jiang and Yiwen Qin for assistance with data collection. We are also grateful to prof. Naidong Wang and prof. Aibing Wang for critical reading of the manuscript.

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

摘要：

Introduction: Over the past two decades, virus-like particles (VLPs) have been developed as a new generation of vaccines against viral infections. Based on VLPs, chimeric VLPs (chi–VLPs) have been generated through genetic modifications or chemical couplings. For construction of multivalent chi–VLPs vaccines, multiple genetic engineering strategies are continuously being developed. Thus, it is important to provide a summary as reference for researchers in this field. Areas covered: The representative studies on the genetic engineered multival...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Genetic engineering strategies for construction of multivalent chimeric VLPs vaccines

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问