A novel design to immobilize the stationary phase for micro-HPLC and capillary electrochromatography has been initially attempted. Porous temporary frit in fused silica capillary was rapidly fabricated by sintering stainless steel powders rapidly, which could withstand a high pressure up to 60 MPa during slurry packing. A mixture of monomer and porogenic solvents such as silica-based and organic-based monomers were pumped into the packed capillary, respectively, followed a quick polymerization by microwave irradiation. The sol-gel network and organic matrix were strong enough to hold back the ...
