Malondialdehyde (MDA) is one of the active carbonyl compounds existing in human body, which can react with protein to form age pigment fluorescence products (APFs) by carbonyl-ammonia cross linking reaction. The purpose of this study is to determine whether tea catechins can inhibit the formation of the age pigment fluorescence products induced by MDA-modified human serum albumin (HSA). Results showed that tea catechins, especially the gallated-catechin, could inhibit the formation of APFs. The structure-activity relationship studies sugg...