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Characterization and Function Analysis of miRNA Editing during Fat Deposition in Chinese Indigenous Ningxiang Pigs

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成果类型:
期刊论文
作者:
Lv, Jiayu;Yang, Fang;Li, Yiyang;Gao, Ning;Zeng, Qinghua;...
通讯作者:
He, Jun;Zhang, YB
作者机构:
[Gao, Ning; He, Jun; Ma, Haiming; Zhang, Yuebo; Yang, Fang; Li, Yiyang; Lv, Jiayu; He, J; Zeng, Qinghua] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Peoples R China.
[Gao, Ning; He, Jun; Ma, Haiming; Zhang, Yuebo; Yang, Fang; Li, Yiyang; Lv, Jiayu; He, J; Zeng, Qinghua] Minist Agr & Rural Affairs, Key Lab Livestock & Poultry Resources Pig Evaluat, Changsha 410000, Peoples R China.
通讯机构:
[Zhang, YB ; He, J] H
Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Peoples R China.
Minist Agr & Rural Affairs, Key Lab Livestock & Poultry Resources Pig Evaluat, Changsha 410000, Peoples R China.
语种:
英文
关键词:
Ningxiang pigs;miRNA editing;high-throughput sequencing;fat deposition
期刊:
Veterinary Sciences
ISSN:
2306-7381
年:
2024
卷:
11
期:
4
页码:
183-
基金类别:
Conceptualization, J.H. and Y.Z.; Methodology, J.L., Y.Z. and F.Y.; Software, Y.Z., J.L., F.Y. and Y.L.; Resources, Q.Z. and H.M.; Data curation, J.L., F.Y. and Y.L.; Writing—original draft, J.L.; Writing—review and editing, J.L., F.Y., Y.L., J.H. and Y.Z.; Supervision, Y.Z., N.G. and J.H.; Project administration, Y.Z., N.G. and J.H.; Funding acquisition, Y.Z., N.G. and J.H. All authors have read and agreed to the published version of the manuscript. This study was funded by the Natural Science Foundation of Hunan Province (2021JJ40254), the Excellent Youth Project of Hunan Provincial Department of Education (22B0209), and the Special Fund for the Construction of Innovative Provinces in Hunan (2021NK1009).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
摘要:
This study aimed to identify active miRNA editing sites during adipose development in Ningxiang pigs and analyze their characteristics and functions. Based on small RNA-seq data from the subcutaneous adipose tissues of Ningxiang pigs at four stages—30 days (piglet), 90 days (nursery), 150 days (early fattening), and 210 days (late fattening)—we constructed a developmental map of miRNA editing in the adipose tissues of Ningxiang pigs. A total of 505 miRNA editing sites were identified using the revised pipeline, with C-to-U editing types being...

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