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Three-Component Cascade Bis-heteroannulation of Aryl or Vinyl Methylketoxime Acetates toward Thieno[3,2-c]isoquinolines

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成果类型:
期刊论文
作者:
Xu, Zhenhua;Deng, Guo-Jun*;Zhang, Feng;Chen, Hongbiao;Huang, Huawen*
通讯作者:
Deng, Guo-Jun;Huang, Huawen
作者机构:
[Chen, Hongbiao; Deng, GJ; Huang, Huawen; Deng, Guo-Jun; Xu, Zhenhua; Zhang, Feng] Xiangtan Univ, Minist Educ, Key Lab Environmentally Friendly Chem & Applicat, Coll Chem,Key Lab Green Organ Synth & Applicat Hu, Xiangtan 411105, Peoples R China.
[Zhang, Feng] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Deng, GJ; Huang, HW] X
Xiangtan Univ, Minist Educ, Key Lab Environmentally Friendly Chem & Applicat, Coll Chem,Key Lab Green Organ Synth & Applicat Hu, Xiangtan 411105, Peoples R China.
语种:
英文
期刊:
Organic Letters
ISSN:
1523-7060
年:
2019
卷:
21
期:
21
页码:
8630-8634
基金类别:
Support by the National Natural Science Foundation of China (21602187 and 21871226), the Science and Technology Planning Project of Hunan Province (2019RS2039), the China Postdoctoral Science Foundation (2019T120709), the Hunan Provincial Innovative Foundation of Postgraduate (CX20190482 and XDCX2019B091), and the Collaborative Innovation Center of New Chemical Technologies for Environmental Benignity and Efficient Resource Utilization is gratefully acknowledged.
机构署名:
本校为其他机构
院系归属:
理学院
摘要:
A three-component cascade bis-heteroannulation reaction is described that provides access to a variety of benzo[4,5]thieno[3,2-c]isoquinoline and thieno[3,2-c]isoquinoline compounds from easily available methylketoximes, o-halobenzaldehydes, and elemental sulfur. Mechanistic studies reveal a two-step process involving a seque...

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