Excretion, Metabolism, and Tissue Distribution of Gelsemium elegans (Gardn. & Champ.) Benth in Pigs

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成果类型：

期刊论文

作者：

Ma, Xiao;Wang, Zi-Yuan;Zuo, Meng-Ting;Yang, Kun;Sun, Zhi-Liang;...

通讯作者：

Wu, Yong;Liu, ZY;Wu, Y

作者机构：

[Wu, Yong; Wang, Zi-Yuan; Sun, Zhi-Liang; Yang, Kun; Liu, Zhao-Ying; Wu, Y; Ma, Xiao; Zuo, Meng-Ting] Hunan Agr Univ, Coll Vet Med, 1 Nongda Rd, Changsha 410128, Peoples R China.

[Wang, Zi-Yuan; Sun, Zhi-Liang; Yang, Kun; Liu, Zhao-Ying; Ma, Xiao; Zuo, Meng-Ting] Hunan Agr Univ, Hunan Engn Technol Res Ctr Vet Drugs, 1 Nongda Rd, Changsha 410128, Peoples R China.

[Wu, Yong; Wu, Y] Hunan Canzoho Biol Technol Co Ltd, Dist Econ & Technol Dev, 321 Kangning Rd, Liuyang 410329, Peoples R China.

通讯机构：

[Wu, Y ; Wu, Y; Liu, ZY ] H

Hunan Agr Univ, Coll Vet Med, 1 Nongda Rd, Changsha 410128, Peoples R China.

Hunan Agr Univ, Hunan Engn Technol Res Ctr Vet Drugs, 1 Nongda Rd, Changsha 410128, Peoples R China.

Hunan Canzoho Biol Technol Co Ltd, Dist Econ & Technol Dev, 321 Kangning Rd, Liuyang 410329, Peoples R China.

语种：

英文

关键词：

alkaloid;plant extract;animal;chemistry;Gelsemium;high performance liquid chromatography;male;pig;tissue distribution;Alkaloids;Animals;Chromatography, High Pressure Liquid;Gelsemium;Male;Plant Extracts;Swine;Tissue Distribution

期刊：

Molecules

ISSN：

1420-3049

年：

2022

卷：

期：

页码：

2605-

DOI：

10.3390/molecules27082605

基金类别：

Funding: This research was funded by the National Natural Science Foundation of China (Grant No.31972737) and the Double first-class construction project of Hunan Agricultural University (No.kxk201801008).

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

摘要：

Gelsemium elegans (Gardn. & Champ.) Benth is a toxic flowering plant in the family Logani-aceae used to treat skin diseases, neuralgia and acute pain. The high toxicity of G. elegans restricts its development and clinical applications, but in veterinary applications, G. elegans has been fed to pigs as a feed additive without poisoning. However, until now, the in vivo processes of the multiple components of G. elegans have not been studied. This study investigates the excretion, metabolism and tissue distribution of the multiple components of G....

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Excretion, Metabolism, and Tissue Distribution of Gelsemium elegans (Gardn. & Champ.) Benth in Pigs

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