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Xinyang flavivirus, from Haemaphysalis flava ticks in Henan Province, China, defines a basal, likely tick-only Orthoflavivirus clade

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成果类型:
期刊论文
作者:
Wang, Lan-Lan;Cheng, Qia;Newton, Natalee D.;Wolfinger, Michael T.;Morgan, Mahali S.;...
通讯作者:
Cheng, TY;Khromykh, Alexander A.;Parry, RH;Khromykh, AA
作者机构:
[Cheng, TY; Cheng, Tian-Yin; Wang, Lan-Lan] Hunan Agr Univ, Coll Vet Med, Changsha, Hunan, Peoples R China.
[Cheng, Qia] Hunan Prov Peoples Hosp, Childrens Med Ctr, Changsha, Peoples R China.
[Newton, Natalee D.; Parry, Rhys H.; Parry, RH; Morgan, Mahali S.; Khromykh, Alexander A.; Slonchak, Andrii] Univ Queensland, Sch Chem & Mol Biosci, Brisbane, Qld, Australia.
[Newton, Natalee D.; Khromykh, Alexander A.; Slonchak, Andrii] Univ Queensland, Australian Infect Dis Res Ctr, Brisbane, Qld, Australia.
[Wolfinger, Michael T.] Univ Vienna, Dept Theoret Chem, Vienna, Austria.
通讯机构:
[Khromykh, AA ; Khromykh, AA; Parry, RH ] U
[Cheng, TY ] H
Hunan Agr Univ, Coll Vet Med, Changsha, Hunan, Peoples R China.
Univ Queensland, Sch Chem & Mol Biosci, Brisbane, Qld, Australia.
Univ Queensland, Australian Infect Dis Res Ctr, Brisbane, Qld, Australia.
语种:
英文
关键词:
Binjari virus;chimeric virus;Flavivirus;Haemaphysalis flava;orthoflavivirus;structural RNA;tick-borne orthoflavivirus;tick-borne pathogen;xrRNA
期刊:
JOURNAL OF GENERAL VIROLOGY
ISSN:
0022-1317
年:
2024
卷:
105
期:
5
基金类别:
Key Research and Development Program of Hunan Province [2019NK2181]; Natural Science Foundation of Hunan Province [2023JJ30287]; Austrian Science Fund FWF [I 6440-N]
机构署名:
本校为第一且通讯机构
院系归属:
动物医学院
摘要:
Tick-borne orthoflaviviruses (TBFs) are classified into three conventional groups based on genetics and ecology: mammalian, seabird and probable-TBF group. Recently, a fourth basal group has been identified in Rhipicephalus ticks from Africa: Mpulungu flavivirus (MPFV) in Zambia and Ngoye virus (NGOV) in Senegal. Despite attempts, isolating these viruses in vertebrate and invertebrate cell lines or intracerebral injection of newborn mice with virus-containing homogenates has remained unsuccessful. In this study, we report the discovery of Xinyang flavivirus (XiFV) in Haemaphysalis flava ticks ...

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