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miR-10b promotes porcine immature Sertoli cell proliferation by targeting the DAZAP1 gene

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成果类型:
期刊论文
作者:
Weng Bo;Ran Mao-liang;Cao Rong;Peng Fu-zhi;Luo Hui;...
通讯作者:
Chen Bin
作者机构:
[Yang An-qi; Weng Bo; Ran Mao-liang; Chen Bin; Gao Hu; Cao Rong; Tang Xiang-wei; Peng Fu-zhi; Luo Hui] Hunan Agr Univ, Hunan Prov Key Lab Genet Improvement Domest Anim, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Chen Bin] H
Hunan Agr Univ, Hunan Prov Key Lab Genet Improvement Domest Anim, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.
语种:
英文
关键词:
miR-10b;DAZAP1;gene expression;proliferation;porcine immature Sertoli cell
期刊:
农业科学学报(英文)
ISSN:
2095-3119
年:
2019
卷:
18
期:
8
页码:
1924-1935
基金类别:
This work was financially supported by the earmarked fund for China Agriculture Research System (CARS-36) and the Hunan Provincial Natural Science Foundation of China (2018JJ2176 and 2018JJ3219).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
摘要:
MicroRNAs (miRNAs) have been widely identified in porcine testicular tissues and implicated as crucial regulators of proliferation, apoptosis, and differentiation in porcine spermatogenesis related cells. However, the function roles of most of the miRNAs that have been identified in Sertoli cells are poorly understood. In the present study, six experiments were conducted to study the regulatory role of miR-10b in porcine immature Sertoli cells. In experiment 1, the results showed that the relative mRNA expression level of miR-10b in porcine tes...

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