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Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows

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成果类型:
期刊论文
作者:
Wang, Yan;Han, Xuefeng;Tan, Zhiliang;Kang, Jinhe*;Wang, Zheng*
通讯作者:
Kang, Jinhe;Wang, Zheng
作者机构:
[Tan, Zhiliang; Han, Xuefeng; Wang, Yan; Kang, Jinhe] Chinese Acad Sci, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Hunan Prov Key Lab Anim Nutr & Physiol & Metab, Inst Subtrop Agr,CAS Key Lab Agroecol Proc Subtro, Changsha 410125, Peoples R China.
[Wang, Zheng; Wang, Yan] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.
[Wang, Yan] Hunan Univ Humanities Sci & Technol, Coll Agr & Biotechnol, Loudi 417000, Peoples R China.
通讯机构:
[Kang, Jinhe] C
[Wang, Zheng] H
Chinese Acad Sci, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Hunan Prov Key Lab Anim Nutr & Physiol & Metab, Inst Subtrop Agr,CAS Key Lab Agroecol Proc Subtro, Changsha 410125, Peoples R China.
Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.
语种:
英文
关键词:
cow;endometrium;involution;rumen-protected glucose
期刊:
ANIMALS
ISSN:
2076-2615
年:
2020
卷:
10
期:
2
页码:
357-
基金类别:
Conceptualization, Y.W., Z.W., and J.K.; methodology, Y.W.; analysis, Y.W., and J.K.; Writing—original draft preparation, Y.W.; writing—review and editing, Z.W., Z.T., X.H., and J.K.; Supervision, Z.T.; project administration, Z.T. and X.H.; funding Acquisition, Z.T. All authors have read and agreed to the published version of the manuscript. The authors acknowledge the financial support received from the National Key Research and Development Program of China (Grant No. 2016YFD0501206, 2016YFD0501206, and 2018YFD0501604), Major Project of Hunan Province (Grant No. 2017NK1020), and CAS Science and Technology Service Network Initiative (Grant No. KFJ-STS-ZDTP-056).
机构署名:
本校为通讯机构
院系归属:
生物科学技术学院
摘要:
This study aimed to elucidate the effects of a dietary rumen-protected glucose (RPG) addition on uterine involution through the analysis of an insulin-like growth factor (IGF) system and associated pathways in the post-natal endometrium. Twelve Holstein cows were assigned equally to two groups: a control group (CT) and an RPG group (200 g of RPG per cow per day). The plasma content of insulin-like growth factor 1 (IGF1) was determined by using the ELISA method. Expressions of IGF members, the matrix metalloproteinase, protein kinase B (AKT)/mec...

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