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Heterogeneity of class I and class II MHC sequences in Schistosoma japonicum from different endemic regions in mainland China

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成果类型:
期刊论文
作者:
Zhao, G. H.;Li, J.;Zou, F. C.;Liu, W.;Mo, X. H.;...
通讯作者:
Zhu, X. Q.
作者机构:
[Song, H. Q.; Zhao, G. H.; Weng, Y. B.; Mo, X. H.; Li, J.; Lin, R. Q.; Yuan, Z. G.; Zhu, X. Q.] S China Agr Univ, Coll Vet Med, Parasitol Lab, Guangzhou 510642, Guangdong, Peoples R China.
[Zou, F. C.] Yunnan Agr Univ, Coll Anim Sci & Technol, Kunming 650201, Yunnan Province, Peoples R China.
[Liu, W.] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.
[Zhu, X. Q.] S China Agr Univ, Coll Vet Med, Parasitol Lab, 483 Wushan St, Guangzhou 510642, Guangdong, Peoples R China.
通讯机构:
[Zhu, X. Q.] S
S China Agr Univ, Coll Vet Med, Parasitol Lab, 483 Wushan St, Guangzhou 510642, Guangdong, Peoples R China.
语种:
英文
关键词:
Major Histocompatibility Complex;Schistosoma;Major Histocompatibility Complex Gene;Schistosoma Japonicum;Unweighted Pair Group Method With Arithmetic Average
期刊:
Parasitology Research
ISSN:
0932-0113
年:
2009
卷:
106
期:
1
页码:
201-206
基金类别:
National Basic Research Program (973 program) of China [2007CB513104]; Program for Changjiang Scholars and Innovative Research Team in University [IRT0723]
机构署名:
本校为其他机构
院系归属:
动物医学院
摘要:
The present study examined sequence variation in class I and class II major histocompatibility complex (MHC) genes among Schistosoma japonicum isolates from different endemic regions in mainland China and assessed the level of horizontal gene transfer and sequence similarity between parasites and their hosts. S. japonicum cercariae were used to infect male adult rabbits to obtain adult S. japonicum samples. A portion of the class I MHC gene (pMHC I) and class II MHC genes (pMHC II) were amplified separately from individual adult trematodes by p...

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