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Abnormal adipose tissue-derived microbes drive metabolic disorder and exacerbate postnatal growth retardation in piglet

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成果类型:
期刊论文
作者:
Tongxing Song;Ming Qi;Yucheng Zhu;Nan Wang;Zhibo Liu;...
通讯作者:
Jinshui Zheng<&wdkj&>Bie Tan
作者机构:
College of Animal Science and Technology, Hunan Agricultural University , Changsha, Hunan 410000 , China
Laboratory of Animal Nutritional Physiology and Metabolic Process, CAS Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences , Changsha, Hunan 410125 , China
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University , Wuhan, Hubei 430070 , China
Hubei Key Laboratory of Agricultural Bioinformatics, Huazhong Agricultural University , Wuhan, Hubei 430070 , China
[Tongxing Song; Yucheng Zhu; Zhibo Liu; Jiacheng Yang; Yanxu Han; Shiyu Tao; Zhuqing Ren] College of Animal Science and Technology, Huazhong Agricultural University , Wuhan, Hubei 430070 , China
通讯机构:
[Jinshui Zheng] S
[Bie Tan] C
College of Animal Science and Technology, Hunan Agricultural University , Changsha, Hunan 410000 , China<&wdkj&>Laboratory of Animal Nutritional Physiology and Metabolic Process, CAS Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences , Changsha, Hunan 410125 , China<&wdkj&>State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University , Wuhan, Hubei 430070 , China<&wdkj&>Hubei Key Laboratory of Agricultural Bioinformatics, Huazhong Agricultural University , Wuhan, Hubei 430070 , China
语种:
英文
关键词:
adipose tissue;microbe;metabolic disorder;postnatal growth retardation;piglet
期刊:
Life Metabolism
ISSN:
2097-2555
年:
2024
卷:
3
期:
2
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
摘要:
Postnatal growth retardation (PGR) frequently occurs during early postnatal development of piglets and induces high mortality. To date, the mechanism of PGR remains poorly understood. Adipose tissue-derived microbes have been documented to be associated with several disorders of metabolism and body growth. However, the connection between microbial disturbance of adipose tissue and pig PGR remains unclear. Here, we investigated piglets with PGR and found that the adipose tissue of PGR piglets was characterized by metabolism impairment, adipose a...

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