期刊论文

Chen, Chunyan;Cai, Changqun

英文

Sensors and Actuators B-Chemical

0925-4005

2019

291

42-47

10.1016/j.snb.2019.04.015

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21775132, 21505112]; Scientific Research Foundation of Hunan Provincial Education DepartmentHunan Provincial Education Department [16A204]; National Natural Science Foundation of Hunan provinceNatural Science Foundation of Hunan Province [2018JJ2388]

本校为其他机构

In this work, a simple, enzyme-free and ultrasensitive resonance light scattering (RLS) method was developed based on graphene quantum dots (GQDs) with a catalytic hairpin assembly amplification strategy for selective detection of mutant DNA. This method contains two probes, GQDs-H1 and GQDs-H2. Two partially complementary hairpins (H1 and H2) are ingeniously and rationally designed, and they can't spontaneously hybridize with each other in the absence of target. When the target is added, the target binds with GQDs-H1 and forms GQDs-H1: target ...