期刊论文

DRUG RESISTANCE AND MULTI-LOCUS SEQUENCE TYPING OF ENTEROCOCCUS FAECALIS STRAINS ISOLATED FROM PIGS AND CHICKENS IN HUNAN PROVINCE

中文

中国动物传染病学报

1674-6422

2020

28

6

102-107

本校为第一机构

为探究湖南省不同地区猪、鸡源粪肠球菌耐药特征,多重耐药株的流行性和多位点序列的分型,本研究采用微量肉汤稀释法对81株分离的粪肠球菌进行8种抗菌药物的耐药性检测,应用MLST方法对部分多重耐药菌株进行分型。结果显示,分离株对红霉素、四环素以及头孢西丁严重耐药,耐药率均在90%以上,对氧氟沙星和氟苯尼考的耐药相对严重,耐药率为60%～80%,仅有1株对万古霉素耐药;本次试验中有75株粪肠球菌对3种及3种以上药物耐药,多重耐药率达92.6%;35株多重耐药粪肠球菌共有21个MLST型,其中CC（Clonal complex）16、CC480、CC476、CC4为优势克隆群。CC16所覆盖的粪肠球菌数量最多,占比28.6%。比较4个优势CC...

The objectives of the present study were to gain more knowledge of the drug resistant characteristics of 81 Enterococcus faecalis strains isolated from pigs and chickens in different regions of Hunan province,prevalence of multi-drug resistant isolates and multi-site sequence types.These strains were tested using the microdilution broth method for their drug resistance to 8 antibiotics and MLST method to further classify those multi-drug resistant strains.The results showed that 90%tested strains were highly resistant to erythromycin,tetracycline and cefoxitin,and 60%to 80%strains were resista...