Dietary supplement with nucleotides in the form of uridine monophosphate or uridine stimulate intestinal development and promote nucleotide transport in weaned piglets.

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成果类型：

期刊论文

作者：

Xie, Chun-yan;Wang, Qinhua;Li, Guanya;Fan, Zhiyong;Wang, Hong;...

通讯作者：

Wu, Xin

作者机构：

[Xie, Chun-yan] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha, Hunan, Peoples R China.

[Li, Guanya; Wang, Qinhua; Wu, Xin] Chinese Acad Sci, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg, Changsha 410125, Hunan, Peoples R China.

[Li, Guanya; Wang, Qinhua; Wu, Xin] Hunan Prov Engn Res Ctr Hlth Live Stock & Poultry, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Changsha, Hunan, Peoples R China.

[Li, Guanya; Wang, Qinhua; Fan, Zhiyong] Hunan Agr Univ, Coll Anim Sci & Technol, Hunan Coinnovat Ctr Safety Anim Prod, Changsha, Hunan, Peoples R China.

[Wang, Hong] Meiya Haian Pharmaceut Co Ltd, Haian, Peoples R China.

通讯机构：

[Wu, Xin] C

Chinese Acad Sci, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg, Changsha 410125, Hunan, Peoples R China.

语种：

英文

关键词：

claudin 1;nucleotide;uridine;uridine phosphate;animal;dietary supplement;female;genetics;growth, development and aging;intestine mucosa;male;metabolism;pig;small intestine;transport at the cellular level;weaning;Animals;Biological Transport;Claudin-1;Dietary Supplements;Female;Intestinal Mucosa;Intestine, Small;Male;Nucleotides;Swine;Uridine;Uridine Monophosphate;Weaning

期刊：

Journal of the Science of Food and Agriculture

ISSN：

0022-5142

年：

2019

卷：

期：

页码：

6108-6113

DOI：

10.1002/jsfa.9850

基金类别：

This article was jointly supported by grants from the National Key Research and Development Program of China (2016YFD0500504), Hunan Provincial Natural Science Foundation of China (2019JJ50268), the earmarked fund for China Agriculture Research System (CARS-35), the earmarked fund for development of science and technology of Guangdong province (2017B090904008), Agricultural innovation project of Hunan Province (2019TD01), Science and Technology Service Network Initiative program of the Chinese Academy of Sciences (KFJ-STS-QYZX-031).

机构署名：

本校为第一机构

院系归属：

动物科学技术学院

生物科学技术学院

摘要：

BACKGROUND: Nucleotides are key constituents of milk, where they are utilized in cell replication, although there are limited studies for weaned piglets. This study evaluated the effects of uridine monophosphate (UMP) with uridine (UR) feed supplementation on the intestinal development and nucleotide transport in weaned piglets. RESULTS: Supplementation with UMP significantly increased (P < 0.05) plasma glucose, and UR supplementation significantly reduced (0.05 < P < 0.10) the plasma total cholesterol (TC) of piglets when compared with that of...

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Dietary supplement with nucleotides in the form of uridine monophosphate or uridine stimulate intestinal development and promote nucleotide transport in weaned piglets.

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