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Deciphering the miRNA transcriptome of granulosa cells from dominant and subordinate follicles at first follicular wave in goat

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成果类型:
期刊论文
作者:
Meng, Jinzhu;Zhao, Yuanyuan;Song, Xingchao;An, Qingming;Wu, Zhenyang
通讯作者:
Zhao, YY
作者机构:
[Meng, Jinzhu; Song, Xingchao; An, Qingming; Zhao, Yuanyuan; Wu, Zhenyang] Tongren Univ, Key Lab Biodivers Conservat & Utilizat Fanjing Mt, Tongren, Guizhou, Peoples R China.
[Meng, Jinzhu] Hunan Agr Univ, Coll Vet Med, Changsha, Peoples R China.
通讯机构:
[Zhao, YY ] T
Tongren Univ, Key Lab Biodivers Conservat & Utilizat Fanjing Mt, Tongren, Guizhou, Peoples R China.
语种:
英文
关键词:
Goat;follicle development;small RNA sequencing;miRNA;target gene
期刊:
Animal Biotechnology
ISSN:
1049-5398
年:
2023
卷:
35
期:
1
页码:
1-10
基金类别:
Guizhou Provincial Education Department Youth Talent Development Project [068, 166]; Guizhou Science and Technology Project (Qian Kehe Foundation) [[2020]1Y138]; Guizhou Thousand Level Innovative Talent Project [2022-[2020]-044]; Doctoral Research Initiation Fundation of Tongren University [trxyDH2001]; Science and Technology Program of Guizhou Province [2020-1Y029]; Science and Technology Planning Project of Tongren [80]
机构署名:
本校为其他机构
院系归属:
动物医学院
摘要:
In goats, most follicles in the ovaries will be atresia and only a few dominant follicles (DFs) may eventually mature and ovulate at a follicular wave. To investigate the potential microRNAs (miRNAs) that regulate the expression of genes associated with follicular dominance or atresia, small RNA sequencing was performed on granulosa cells of DF and subordinate follicle at the first follicular wave in goats. A total of 108 differentially expressed miRNAs were detected in the two types of follicle granulosa cells: 16 upregulated miRNAs and 92 downregulated miRNAs. Kyoto Encyclopedia of Genes and...

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