期刊论文

Gong, Zhihua;Xiao, WJ

英文

Food and Chemical Toxicology

0278-6915

2023

181

114095

10.1016/j.fct.2023.114095

This work was supported by the Natural Science Foundation of Hunan Province, China (2020JJ4036), National Key Research and Development Program of China (2017YFD0400803), and the Key R&D Program of Hunan Province (2021NK2016). CRediT authorship contribution statement Yangling Zhang: Design and implementation of experiments, analyzing data, and drafting manuscripts; Yuxin Song: Assisting in animal experiments; Jiao Zhang, Lanlan Li, and Lin He: Collecting samples and interpreting data; Jiahui Bo: Literature retrieval and proofreading; Zhihua Gong and Wenjun Xiao: Designing projects, obtaining funding, assisting with writing and manuscript finalization. All authors have read and approved the final version of the manuscript.

本校为第一且通讯机构

The protein levels in a diet are correlated with immunity but the long-term intake of excessive protein can compromise various aspects of health. L-theanine regulates immunity and protein metabolism; however, how its regulatory immunity effects under a high-protein diet are unclear. We used proteomics, metabonomics, and western blotting to analyze the effects of diets with different protein levels on immune function in rats to determine the role of L-theanine in immunity under a high-protein diet. The long-term intake of high-protein diets (>= 40% protein) promoted oxidative imbalance and infl...