Synthesis, Characterization, and Evaluation of Genistein-Loaded Zein/Carboxymethyl Chitosan Nanoparticles with Improved Water Dispersibility, Enhanced Antioxidant Activity, and Controlled Release Property

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成果类型：

期刊论文

作者：

Xiao, Yu;Ho, Chi-Tang;Chen, Yulian;Wang, Yuanliang;Wei, Zihao;...

通讯作者：

Dong, Mingsheng;Huang, Qingrong

作者机构：

[Xiao, Yu; Wang, Yuanliang] Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.

[Dong, Mingsheng; Xiao, Yu] Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Peoples R China.

[Xiao, Yu; Ho, Chi-Tang; Huang, Qingrong; Wei, Zihao] Rutgers State Univ, Dept Food Sci, 65 Dudley Rd, New Brunswick, NJ 08901 USA.

[Chen, Yulian] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Peoples R China.

通讯机构：

[Dong, Mingsheng] N

[Huang, Qingrong] R

Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Peoples R China.

Rutgers State Univ, Dept Food Sci, 65 Dudley Rd, New Brunswick, NJ 08901 USA.

语种：

英文

关键词：

genistein;zein;carboxymethyl chitosan;nanoparticles;water dispersibility;stability

期刊：

Foods

ISSN：

2304-8158

年：

2020

卷：

期：

页码：

1604

DOI：

10.3390/foods9111604

基金类别：

China Scholarship CouncilChina Scholarship Council [201606850017]; Rutgers University Joint Ph. Program Scholarships [P-1-00737, N0020424829]

机构署名：

本校为第一机构

院系归属：

动物科学技术学院

食品科学技术学院

摘要：

Genistein is one of major isoflavones derived from soybean products and it is believed to have beneficial effects on human health. However, its low water-solubility and poor oral bioavailability severely hamper its use as a functional food ingredient or for pharmaceutical industry. In this study, zein and zein/carboxymethyl chitosan (CMCS) nanoparticles were prepared to encapsulate genistein using a combined liquid–liquid phase separation method. The physicochemical properties of fabricated nanoparticles were characterized by dynamic light sca...

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Synthesis, Characterization, and Evaluation of Genistein-Loaded Zein/Carboxymethyl Chitosan Nanoparticles with Improved Water Dispersibility, Enhanced Antioxidant Activity, and Controlled Release Property

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