Conceptualization, D.W., N.D.E., and Y.Y.; methodology, D.W. and J.M.; software, D.W. and Y.Z.; validation, D.W., W.Z., W.Y., and J.M.; formal analysis, D.W. and Y.Y.; investigation, D.W. and Y.Y.; resources, W.Z., W.Y., and J.M.; data curation, D.W., N.W., and Y.Y.; writing—original draft preparation, D.W.; writing—review and editing, N.W., N.D.E., and Y.Y.; visualization, D.W., N.E., and Y.Y.; supervision, Y.Y.; project administration, Y.Y.; funding acquisition, Y.Z., N.W., and Y.Y. All authors have read and agreed to the published version of the manuscript. This research was funded by the Hunan Provincial Key Laboratory of Protein Engineering in Animal Vaccine, grant number 2017TP1014; the Hunan Education Department’s Science & Research Project, grant number 18B092; the Hunan Provincial Natural Science Foundation of China, grant number 2018JJ2177; and the Double first-class construction project of Hunan Agricultural University, grant number SYL2019048. N.D.E. was supported by the Intramural Institute of the NHLBI, NIH, Bethesda, MD, USA.
