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In silico analyses of antigenicity and surface structure variation of an emerging porcine circovirus genotype 2b mutant, prevalent in southern China from 2013 to 2015

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成果类型:
期刊论文
作者:
Zhan, Yang;Wang, Naidong;Zhu, Zhe;Wang, Zhanfeng;Wang, Aibing;...
通讯作者:
Yang, Yi
作者机构:
[Zhan, Yang; Wang, Naidong; Wang, Aibing; Zhu, Zhe; Deng, Zhibang; Wang, Zhanfeng; Yang, Yi] Hunan Agr Univ, Res Ctr Funct Prote, Coll Vet Med, Changsha, Hunan, Peoples R China.
通讯机构:
[Yang, Yi] H
Hunan Agr Univ, Res Ctr Funct Prote, Coll Vet Med, Changsha, Hunan, Peoples R China.
语种:
英文
期刊:
JOURNAL OF GENERAL VIROLOGY
ISSN:
0022-1317
年:
2016
卷:
97
期:
4
页码:
922-933
机构署名:
本校为第一且通讯机构
院系归属:
动物医学院
摘要:
Porcine circovirus type 2 (PCV2) is the pivotal pathogen causing porcine circovirus-associated diseases. In this study, 62 PCV2 isolates were identified from seven farms in southern China from 2013 to 2015 and phylogenetic trees were reconstructed based on whole-genome sequences or the cap gene. In this investigation, PCV2b was the main genotype in circulation throughout these farms. Furthermore, an emerging mutant (PCV2b-1C), isolated from PCV2-vaccinated farms, was the predominant strain prevalent on these farms. In addition, we isolated a ne...

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