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Molecular characterization of an NADPH cytochrome P450 reductase from Bemisia tabaci Q: Potential involvement in susceptibility to imidacloprid

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成果类型:
期刊论文
作者:
He, Chao;Liang, Jinjin;Liu, Shaonan;Zeng, Yang;Wang, Shaoli;...
通讯作者:
Xie, Wen;Zhang, Youjun
作者机构:
[Liu, Shaonan; Xie, Wen; Zhang, Youjun; Wang, Shaoli; He, Chao; Wu, Qingjun; Xie, W; Zhang, YJ; Zeng, Yang] Chinese Acad Agr Sci, Inst Vegetables & Flowers, Dept Plant Protect, Beijing 100081, Peoples R China.
[Liang, Jinjin] Hunan Agr Univ, Coll Plant Protect, Changsha 410128, Peoples R China.
通讯机构:
[Xie, W; Zhang, YJ] C
Chinese Acad Agr Sci, Inst Vegetables & Flowers, Dept Plant Protect, Beijing 100081, Peoples R China.
语种:
英文
关键词:
cytochrome P450;imidacloprid;imidazole derivative;insecticide;neonicotinoid;nitro derivative;reduced nicotinamide adenine dinucleotide phosphate ferrihemoprotein reductase;animal;Hemiptera;insecticide resistance;male;Animals;Cytochrome P-450 Enzyme System;Hemiptera;Imidazoles;Insecticide Resistance;Insecticides;Male;NADPH-Ferrihemoprotein Reductase;Neonicotinoids;Nitro Compounds
期刊:
Pesticide Biochemistry and Physiology
ISSN:
0048-3575
年:
2020
卷:
162
页码:
29-35
基金类别:
This research was supported by the National Research and Development Program ( 2017YFD0200603 ), the National Natural Science Foundation of China ( 31420103919 and 31672032 ), Beijing Nova Program ( Z171100001117039 ), China Agriculture Research System ( CARS-24-C-02 ), the Beijing Key Laboratory for Pest Control and Sustainable Cultivation of Vegetables and the Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences ( CAAS-ASTIP-IVFCAAS ). This research was supported by the National Research and Development Program (2017YFD0200603), the National Natural Science Foundation of China (31420103919 and 31672032), Beijing Nova Program (Z171100001117039), China Agriculture Research System (CARS-24-C-02), the Beijing Key Laboratory for Pest Control and Sustainable Cultivation of Vegetables and the Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences (CAAS-ASTIP-IVFCAAS).
机构署名:
本校为其他机构
院系归属:
植物保护学院
摘要:
NADPH cytochrome P450 reductase (CPR) is an integral component of cytochrome P450-mediated biological reactions, such as the metabolism of xenobiotics, including insecticides. CPR has been reported to be associated with insecticide tolerance in several insects. However, the biochemical characteristics and biological function of CPR in Bemisia tabaci Q (BtCPR) remain undefined. In this study, BtCPR was cloned, and bioinformatic analysis showed that BtCPR is a transmembrane protein with a molecular weight (MW) of 76.73 kDa and contains conserved ...

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