Although the silencing of Aminopeptidase‐N 2 resulted in a significant increase in resistance to Cry1Ac in Plutella xylostella, it also had a significant negative impact on its growth, development, and fecundity. Abstract Bacillus thuringiensis (Bt) is widely used as a biopesticide worldwide. To date, at least eight pest species have been found to be resistant to Bt in the field. As the first pest that was reported having resistance to Bt in the field, considerable research has been done on the mechanisms of Bt resistance in Plutella xylostell...
