Insights from metagenomics on microbial biosynthesis of vitamins B and K2 in chicken gut microbiota

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成果类型：

期刊论文

作者：

Yu, Hai-Long;Hou, Xin-Wen;Zhao, Ji-Xin;Liu, Guo-Hua;Meng, Jin-Xin;...

通讯作者：

Yang, X

作者机构：

[Yang, Xing; Yu, Hai-Long] Dali Univ, Sch Basic Med, Dept Med Microbiol & Immunol, Dali, Yunnan Province, Peoples R China.

[Chen, Bei-Ni; Cai, Yanan; Yu, Hai-Long] Jilin Agr Univ, Coll Vet Med, Changchun, Yunnan Province, Peoples R China.

[Hou, Xin-Wen; Zhao, Ji-Xin; Meng, Jin-Xin; Shang, Kai-Meng; Liu, Rui; Nan, Fu-Long; Ni, Hong-Bo; Ma, He; Liu, Jian; Zhang, Xiao-Xuan; Wei, Yong-Jie] Qingdao Agr Univ, Coll Vet Med, Qingdao, Shandong Provin, Peoples R China.

[Liu, Guo-Hua] Hunan Agr Univ, Coll Vet Med, Res Ctr Parasites & Vectors, Changsha, Peoples R China.

[Meng, Jin-Xin] Zhejiang Univ, Coll Anim Sci, Dept Vet Med, Hangzhou, Zhejiang, Peoples R China.

通讯机构：

[Yang, X ] D

Dali Univ, Sch Basic Med, Dept Med Microbiol & Immunol, Dali, Yunnan Province, Peoples R China.

语种：

英文

关键词：

Vitamins B and K2;Chicken gut microbiome;Metagenomic analysis;cobalamin;Pathogen infection Moreover

期刊：

Frontiers in Veterinary Science

ISSN：

2297-1769

年：

2025

卷：

页码：

1646825

DOI：

10.3389/fvets.2025.1646825

基金类别：

Distinguished Scholar Research Fund of Qingdao Agricultural University [1120046]

机构署名：

本校为其他机构

院系归属：

动物医学院

摘要：

Introduction: The chicken gut microbiome plays a pivotal role in nutrient absorption and overall health, contributing to the biosynthesis of essential vitamins. However, the biosynthesis of vitamins B and K-2 by the whole gut microbiome, as well as their abundances across different gut regions, remains largely unknown. Methods: We employed both metagenomic sequencing and culture-based techniques, collecting a total of 25,825 genomes (25,764 metagenome-assembled genomes and 61 isolated genomes). After quality assessment and average nucleotide identity (ANI), 13,734 genomes were retained for dow...

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Insights from metagenomics on microbial biosynthesis of vitamins B and K2 in chicken gut microbiota

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