Ameliorative Effect of Areca Nut Polyphenols on Adverse Effects Induced by Lipopolysaccharides in RAW264.7 Cells

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成果类型：

期刊论文

作者：

Zou, Luyan;Yi, Shuhan*;Wang, Yuanliang

通讯作者：

Yi, Shuhan;Wang, YL;Yi, SH

作者机构：

[Yi, Shuhan; Zou, Luyan; Wang, YL; Wang, Yuanliang] Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.

[Yi, Shuhan] Kagoshima Univ, United Grad Sch Agr Sci, Kagoshima 8900065, Japan.

[Wang, YL; Wang, Yuanliang] Hunan Prov Key Lab Food Sci & Biotechnol, Changsha 410128, Peoples R China.

[Wang, YL; Wang, Yuanliang] Natl Engn Ctr Plant Funct Components Utilizat, Changsha 410128, Peoples R China.

[Wang, YL; Wang, Yuanliang] Hunan Agr Univ, Changsha Innovat Inst Food, Changsha 410128, Peoples R China.

通讯机构：

[Yi, SH; Wang, YL ] H

[Yi, SH ] K

Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.

Kagoshima Univ, United Grad Sch Agr Sci, Kagoshima 8900065, Japan.

Hunan Prov Key Lab Food Sci & Biotechnol, Changsha 410128, Peoples R China.

语种：

英文

关键词：

cytokine;lipopolysaccharide;plant extract;polyphenol;animal;Areca;mouse;nut;RAW 264.7 cell line;Animals;Areca;Cytokines;Lipopolysaccharides;Mice;Nuts;Plant Extracts;Polyphenols;RAW 264.7 Cells

期刊：

Molecules

ISSN：

1420-3049

年：

2024

卷：

期：

页码：

1329-

DOI：

10.3390/molecules29061329

基金类别：

This research was funded by the Hunan Province Science and Technology Innovation Project (grant no. 2017SK2430) and the Hainan Province Science and Technology Major Project (grant no. ZDKJ2016003).

机构署名：

本校为第一且通讯机构

院系归属：

食品科学技术学院

摘要：

In Asian regions, areca nuts are tropical fruits that are extensively consumed. The areca nut contains a lot of polyphenols and its safety is unknown. In this research, we investigated the effects of lipopolysaccharides (LPS) and areca nut polyphenols (ANP) on normal RAW264.7 cells. The results showed that LPS stimulated adverse effects in normal cells by affecting cytokine production. The GO analysis results mainly affected DNA repair, cell division, and enzyme activities. In the KEGG analysis results, the NOD-like receptor signaling pathway, ...

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Ameliorative Effect of Areca Nut Polyphenols on Adverse Effects Induced by Lipopolysaccharides in RAW264.7 Cells

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