期刊论文

中文

中国兽医杂志

0529-6005

2023

59

11

37-41

31972737:国家自然科学基金

本校为第一机构

为了研究钩吻提取物对猪肝脏细胞色素P450(CYP450)和醌氧化还原酶(NQO1)活性的影响,本试验选用95％乙醇溶液制备钩吻醇提取物和0.5％硫酸溶液制备钩吻酸水提取物,将56日龄仔猪随机分为5个组,每组15只,分别为T1组(基础日粮)、T2组(基础日粮+150 μg/mL钩吻酸水提取物)、T3组(基础日粮+25μg/mL钩吻醇提取物)、T4组(基础日粮+50 μg/mL钩吻醇提取物)和T5组(基础日粮+100 μg/mL钩吻醇提取物),连续饲喂47 d,取肝脏制备微粒体和胞液,通过比色法分析钩吻提取物对肝微粒体中氨基比林-N-脱甲基酶(AND)和红霉素-N-脱甲基酶(ERND)活性的影响,并探究钩吻提取物对肝胞液中NQO1活性的影响.结果显示,与T1组相...

To investigate the impact of Gelsemium elegans extracts on the activities of cytochrome P450(CYP450)and NAD(P)H:quinone oxidoreductase 1(NQO1)in pig liver,this study utilized a 95％ethanol solution to prepare Gelsemium elegans alcohol extract and a 0.5％sulfuric acid solution to prepare Gelsemium elegans water extract.Fifty-six-day-old piglets were randomly divided into five groups,each consisting of 15 piglets:T1 group(basic diet),T2 group(basic diet+150 μg/mL Gelsemium elegans water extract),T3 group(basic diet+25 μg/mL Gelsemium elegans al...