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Jasmine tea extract prevents CUMS-induced depression-like behaviors through the modulation of microbiota-gut-brain axis

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成果类型:
期刊论文
作者:
Zhou, Jiaxin;Zhao, Yiqiao;Li, Yilong;Li, Jie;Huang, Jianan;...
通讯作者:
Liu, Zhonghua;Zhu, MZ;Liu, L
作者机构:
[Zhou, Jiaxin; Liu, Zhonghua; Zhao, Yiqiao; Li, Jie; Huang, Jianan; Zhu, Mingzhi; Li, Yilong] Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredien, Key Lab Tea Sci, Minist Educ, Changsha 410128, Hunan, Peoples R China.
[Liu, Lin] Hunan Univ Chinese Med, Hosp 1, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Liu, ZH; Liu, L ; Zhu, MZ ] H
Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredien, Key Lab Tea Sci, Minist Educ, Changsha 410128, Hunan, Peoples R China.
Hunan Univ Chinese Med, Hosp 1, Changsha 410128, Hunan, Peoples R China.
语种:
英文
关键词:
Depression;Gut microbiota;Jasmine tea extracts;Microbiota–gut–brain axis;Non-targeted metabolomics;Targeted metabolomics
期刊:
Food Research International
ISSN:
0963-9969
年:
2025
卷:
209
页码:
116214
基金类别:
This research was financially supported by the National Key Research and Development Program of China (2022YFD2101103), Natural Science Foundation of China (32172217), the Key Research and Development Program of Hunan Province (2024JK2150), Yunnan Province Key Research and Development Program of China (202202AE090030). CRediT authorship contribution statement Jiaxin Zhou: Writing – original draft, Software, Formal analysis, Data curation. Yiqiao Zhao: Writing – review & editing. Yilong Li: Writing – review & editing. Jie Li: Investigation, Conceptualization. Jianan Huang: Supervision, Resources, Project administration. Lin Liu: Methodology. Zhonghua Liu: Supervision, Resources, Project administration. Mingzhi Zhu: Supervision, Resources, Project administration, acquisition.
机构署名:
本校为第一且通讯机构
院系归属:
园艺园林学院
摘要:
Depression is strongly linked to dysfunctions in the microbiota-gut-brain axis. Jasmine tea, a traditional Chinese beverage made by combining green tea with Jasminum sambac , has potential antidepressant effects. However, its potential to alleviate depression via modulation of the microbiota-gut-brain axis remains largely unstudied. In this study, we used a rat model of depression induced by chronic unpredictable mild stress (CUMS) to investigate the effects of jasmine tea extract (JT) on depression-related symptoms. Behavioral assessments, inf...

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