Opportunities of prebiotics for the intestinal health of monogastric animals
作者:
Azad, Md A. K.;Gao, Jing;Ma, Jie;Li, Tiejun;Tan, Bie;...
期刊:
动物营养(英文) ,2020年6(4):379-388 ISSN:2405-6545
通讯作者:
Yin, Jie
作者机构:
[Yin, Jie; Tan, Bie; Huang, Xingguo; Azad, Md A. K.; Ma, Jie] Hunan Agr Univ, Coll Anim Sci & Technol, Hunan Prov Engn Res Ctr Appl Microbial Resources, Changsha 410128, Peoples R China.;[Gao, Jing; Li, Tiejun; Azad, Md A. K.] Chinese Acad Sci, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Key Lab Agroecol Proc Subtrop Reg,Inst Subtrop Ag, Changsha 410125, Peoples R China.;[Gao, Jing; Azad, Md A. K.] Univ Chinese Acad Sci, Beijing 100049, Peoples R China.
通讯机构:
[Yin, Jie] H;Hunan Agr Univ, Coll Anim Sci & Technol, Hunan Prov Engn Res Ctr Appl Microbial Resources, Changsha 410128, Peoples R China.
关键词:
Prebiotics;Gut microbiota;Intestinal health;Short-chain fatty acids
摘要:
The goal of prebiotic applications from different sources is to improve the gut ecosystem where the host and microbiota can benefit from prebiotics. It has already been recognized that prebiotics have potential roles in the gut ecosystem because gut microbiota ferment complex dietary macronutrients and carry out a broad range of functions in the host body, such as the production of nutrients and vitamins, protection against pathogens, and maintenance of immune system balance. The gut ecosystem is very crucial and can be affected by numerous factors consisting of dietary constituents and commensal bacteria. This review focuses on recent scientific evidence, confirming a beneficial effect of prebiotics on animal health, particularly in terms of protection against pathogenic bacteria and increasing the number of beneficial bacteria that may improve epithelial cell barrier functions. It has also been reviewed that modification of the gut ecosystem through the utilization of prebiotics significantly affects the intestinal health of animals. However, the identification and characterization of novel potential prebiotics remain a topical issue and elucidation of the metagenomics relationship between gut microbiota alteration and prebiotic substances is necessary for future prebiotic studies. (C) 2020, Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
语种:
英文
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Lactobacillus delbrueckii Interfere With Bile Acid Enterohepatic Circulation to Regulate Cholesterol Metabolism of Growing-Finishing Pigs via Its Bile Salt Hydrolase Activity
作者:
Hou, Gaifeng;Peng, Wei;Wei, Liangkai;Li, Rui* ;Yuan, Yong;...
期刊:
FRONTIERS IN NUTRITION ,2020年7:617676 ISSN:2296-861X
通讯作者:
Li, Rui;Huang, Xingguo
作者机构:
[Wei, Liangkai; Hou, Gaifeng; Li, Rui; Huang, Xingguo; Li, R; Huang, XG; Peng, Wei; Yuan, Yong; Yin, Yulong] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Peoples R China.;[Wei, Liangkai; Hou, Gaifeng; Li, Rui; Huang, Xingguo; Li, R; Huang, XG; Peng, Wei; Yuan, Yong; Yin, Yulong] Hunan Coinnovat Ctr Anim Prod Safety, Changsha, Peoples R China.;[Li, Rui; Yin, Yulong] Chinese Acad Sci, Hunan Prov Engn Res Ctr Hlth Livestock & Poultry, Inst Subtrop Agr,Minist Agr, Key Lab Agroecol Proc Subtrop Reg,Sci Observing &, Changsha, Peoples R China.
通讯机构:
[Li, R; Huang, XG] H;[Li, Rui] C;Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Peoples R China.;Hunan Coinnovat Ctr Anim Prod Safety, Changsha, Peoples R China.;Chinese Acad Sci, Hunan Prov Engn Res Ctr Hlth Livestock & Poultry, Inst Subtrop Agr,Minist Agr, Key Lab Agroecol Proc Subtrop Reg,Sci Observing &, Changsha, Peoples R China.
关键词:
: Lactobacillus delbrueckii;ieal microbiota;Cholesterol;Bile acids;Enterohepatic Circulation;pigs 2
摘要:
<jats:p>Microbiota-targeted therapies for hypercholesterolemia get more and more attention and are recognized as an effective strategy for preventing and treating cardiovascular disease. The experiment was conducted to investigate the cholesterol-lowering mechanism of <jats:italic>Lactobacillus delbrueckii</jats:italic> in a pig model. Twelve barrows (38.70 ± 5.33 kg) were randomly allocated to two groups and fed corn–soybean meal diets with either 0% (Con) or 0.1% <jats:italic>Lactobacillus delbrueckii</jats:italic> (Con + LD) for 28 days. <jats:italic>L. delbrueckii–</jats:italic>fed pigs had lower serum contents of total cholesterol (TC), total bile acids (TBAs), and triglyceride, but higher fecal TC and TBA excretion. <jats:italic>L. delbrueckii</jats:italic> treatment increased ileal <jats:italic>Lactobacillus</jats:italic> abundance and bile acid (BA) deconjugation and affected serum and hepatic BA composition. Dietary <jats:italic>L. delbrueckii</jats:italic> downregulated the gene expression of ileal apical sodium-dependent bile acid transporter (<jats:italic>ASBT</jats:italic>) and ileal bile acid binding protein (<jats:italic>IBABP</jats:italic>), and hepatic farnesoid X receptor (<jats:italic>FXR</jats:italic>), fibroblast growth factor (<jats:italic>FGF19</jats:italic>), and small heterodimer partner (<jats:italic>SHP</jats:italic>), but upregulated hepatic high-density lipoprotein receptor (<jats:italic>HDLR</jats:italic>), low-density lipoprotein receptor (<jats:italic>LDLR</jats:italic>), sterol regulatory element binding protein-2 (<jats:italic>SREBP-2</jats:italic>), and cholesterol-7α hydroxylase (<jats:italic>CYP7A1</jats:italic>) expression. Our results provided <jats:italic>in vivo</jats:italic> evidence that <jats:italic>L. delbrueckii</jats:italic> promote ileal BA deconjugation with subsequent fecal TC and TBA extraction by modifying ileal microbiota composition and induce hepatic BA neosynthesis via regulating gut–liver FXR–FGF19 axis.</jats:p>
语种:
英文
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德氏乳杆菌和低聚木糖对环江香猪胴体性状和肉品质的影响
作者:
蔡巧利;唐武;蒋慧姣;黄攀;玉中班;...
期刊:
动物营养学报 ,2020年32(02):636-645 ISSN:1006-267X
作者机构:
[蔡巧利; 孔祥峰; 蒋慧姣] 中国科学院亚热带农业生态研究所,亚热带农业生态过程重点实验室,动物营养生理与代谢过程湖南省重点实验室,长沙 410125;[黄兴国; 蔡巧利; 孔祥峰; 蒋慧姣] 湖南农业大学动物科学技术学院,湖南省畜禽安全生产协同创新中心,长沙 410128;环江毛南族自治县水产畜牧兽医局,环江 547100;[唐武; 黄攀] 中国科学院亚热带农业生态研究所;[玉中班] 环江毛南族自治县水产畜牧兽医局
关键词:
德氏乳杆菌;低聚木糖;环江香猪;胴体性状;肉品质
摘要:
本试验旨在研究德氏乳杆菌(LD)和低聚木糖(XOS)对环江香猪胴体性状和肉品质的影响。选取平均体重为9.5 kg左右的环江香猪96头,随机分为3组,每组8个重复,每个重复4头猪,公母各占1/2。对照组饲喂基础饲粮,德氏乳杆菌组(LD组) 、德氏乳杆菌+低聚木糖组(LD+XOS组)分别在基础饲粮中添加0.05% LD、0.05% LD+0.02% XOS。预试期3 d,正试期84 d。于试验的第28、56和84天(体重分别为15、26和37 kg左右)屠宰测定胴体性状,取背最长肌测定肉品质。结果表明:与对照组相比,试验第28天,LD组背膘厚及肌肉硬脂酸、饱和脂肪酸含量显著降低(P<0.05),LD组肌肉pH_(45 min)显著升高(P<0.05),LD+XOS组眼肌面积及肌肉pH_(45 min) 、粗蛋白质(CP)含量显著升高(P<0.05);试验第56天,LD组肌肉棕榈油酸含量显著升高(P<0.05),LD+XOS组肌肉亮度值和棕榈酸(C16∶0)含量显著降低(P<0.05),LD+XOS组肌肉干物质、CP、花生酸、天冬氨酸、苏氨酸、丝氨酸、甘氨酸、缬氨酸、络氨酸、苯丙氨酸、赖氨酸、组氨酸和精氨酸含量均显著升高(P<0.05);试验第84天,LD组和LD+XOS组皮厚和肌肉亮度值显著降低(P<0.05),LD组肌肉花生烯酸含量显著降低(P<0.05),LD+XOS组背膘厚和肌肉红度值、C16∶0含量显著升高(P<0.05) 。此外,试验第84天,LD组脂肪率显著低于LD+XOS组(P<0.05),肌肉pH_(45 min)显著高于LD +XOS组(P < 0.05) 。上述结果提示,饲粮添加LD和XOS可改善环江香猪的胴体性状、肉品质和肌肉营养成分,且二者同时添加时效果更佳。
语种:
中文
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肠上皮细胞中内质网应激与动物肠道炎症机制的研究进展
作者:
文伟;陈凤鸣;黄兴国;李颖慧
期刊:
动物营养学报 ,2020年32(02):530-539 ISSN:1006-267X
作者机构:
[黄兴国; 文伟; 李颖慧; 陈凤鸣] 湖南农业大学动物科学技术学院,长沙 410128;[黄兴国; 文伟; 李颖慧; 陈凤鸣] 湖南省畜禽安全生产协同创新中心,长沙 410128
关键词:
内质网应激;肠道炎症;未折叠蛋白质;肠上皮细胞
摘要:
近年来,内质网应激参与动物炎症性肠病发病机制的研究引起了广泛关注,未折叠或错误折叠的蛋白质在内质网腔中过量积累而引发内质网应激,持续的内质网应激则会导致动物肠黏膜屏障损伤并诱发肠道炎症。本文就内质网应激发生机制、未折叠蛋白质反应及内质网应激与肠道炎症互作机制进行了综述,旨在为防治动物肠道炎症提出新的治疗策略。
语种:
中文
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构树叶的营养价值及其在动物生产中的应用研究进展
作者:
张红;陈凤鸣;黄兴国;李颖慧
期刊:
动物营养学报 ,2020年32(9):4086-4092 ISSN:1006-267X
作者机构:
[黄兴国; 李颖慧; 张红; 陈凤鸣] 湖南农业大学动物科学技术学院,湖南家禽安全生产工程技术研究中心,湖南畜禽安全生产协同创新中心,长沙 410128
关键词:
构树叶;化学组成;生理功能;应用;综述
摘要:
构树叶含有多种营养物质和天然活性成分,具有抗氧化、抑菌抗炎以及调节糖脂代谢等生物学功能,其作为一种产量可观而价格低廉的非常规饲料资源,在动物生产中有广阔的应用前景。本文综述了构树叶的化学组成、生理功能及其在动物生产中的应用,并提出今后需要进一步研究的问题。
语种:
中文
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凹凸棒石的作用机制及其在动物生产中的应用
作者:
袁勇;文伟;冯智茂;黄兴国
期刊:
动物营养学报 ,2020年32(6):2533-2542 ISSN:1006-267X
作者机构:
[黄兴国; 袁勇; 文伟; 冯智茂] 湖南农业大学动物科学技术学院,长沙 410128;[黄兴国; 袁勇; 文伟; 冯智茂] 湖南省畜禽安全生产协同创新中心,长沙 410128
关键词:
凹凸棒石;改性;作用机制;动物生产;应用
摘要:
凹凸棒石(APT)是一种天然的层链状晶质水合镁铝硅酸盐矿物,具有吸附霉菌毒素、重金属、致病微生物与毒性抗原以及保护消化道黏膜、抗炎、防治腹泻等功效;此外,改性APT还具有抗菌作用。作为功能性饲料原料,APT能提升产品品质、改善机体免疫和抗氧化机能、促进肠道健康、提高饲粮养分利用率和动物生产性能。本文综述了APT的理化性质、常见改性方法、生物学功能及机制以及其应用于动物生产的国内外最新研究成果。
语种:
中文
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中草药药渣在动物生产中的应用
作者:
冯智茂;袁勇;张云飞;黄兴国
期刊:
饲料工业 ,2020年41(10):16-18 ISSN:1001-991X
作者机构:
湖南农业大学动物科学技术学院湖南省畜禽安全生产协同创新中心,湖南长沙410128;[黄兴国; 张云飞; 袁勇; 冯智茂] 湖南农业大学
关键词:
中草药药渣;发酵;新型饲料资源;动物生产;畜禽养殖
摘要:
作为健康绿色养殖的新型饲料资源,中草药药渣因其毒副作用小、安全性高、不产生耐药性等特点已被畜牧业广泛关注。本文综述了中草药药渣的主要成分、发酵工艺及其在动物生产中的应用,以期为中草药药渣的研究应用提供参考。
语种:
中文
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发酵木薯渣的营养价值及其在畜禽生产中的应用进展
作者:
项轩;倪姮佳;黄兴国;李颖慧
期刊:
黑龙江畜牧兽医 ,2020年(19):45-50 ISSN:1004-7034
作者机构:
湖南农业大学动物科学技术学院/湖南畜禽安全生产协同创新中心,长沙410128;中国科学院亚热带农业生态研究所/亚热带农业生态过程重点实验室,长沙410125;[黄兴国; 李颖慧; 项轩] 湖南农业大学;[倪妲佳] 中国科学院亚热带农业生态研究所
关键词:
发酵木薯渣;能量饲料;营养价值;生产应用;微生物发酵
摘要:
木薯渣是生产木薯淀粉和乙醇等产品的下脚料,随着木薯加工产业的快速发展,木薯加工废弃物的产量也逐年增加,造成资源浪费和环境污染。木薯渣含有丰富且易消化的碳水化合物以及多种微量元素、矿物质和氨基酸,是一种来源广泛、价格低廉的能量饲料,但由于粗纤维含量较高且存在抗营养因子而限制了其在饲料中的应用。利用微生物发酵法处理木薯渣可以提高其蛋白质含量、改善适口性,还能有效降低抗营养因子含量,从而提高营养品质和饲用价值。文章就发酵木薯渣的营养组成及其在畜禽生产中的应用展开综述,以期为发酵木薯渣的合理开发利用提供参考。
语种:
中文
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Effects of dietary ramie powder at various levels on growth performance, antioxidative capacity and fatty acid profile of finishing pigs.
作者:
Li, Yinghui;Liu, Yingying;Li, Fengna* ;Sun, Ao;Lin, Qian;...
期刊:
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION ,2019年103(2):564-573 ISSN:0931-2439
通讯作者:
Li, Fengna
作者机构:
[Li, Yinghui; Li, Fengna; Yin, Yulong] Chinese Acad Sci, Key Lab Agroecol Proc Subtrop Reg, Hunan Prov Engn Res Ctr Hlth Livestock & Poultry, Inst Subtrop Agr,Sci Observing & Expt Stn Anim Nu, Changsha, Hunan, Peoples R China.;[Li, Yinghui; Huang, Xingguo] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Hunan, Peoples R China.;[Li, Yinghui; Huang, Xingguo; Li, Fengna] Hunan Coinnovat Ctr Anim Prod Safety, Changsha, Hunan, Peoples R China.;[Sun, Ao; Liu, Yingying] Hunan Inst Anim & Vet Sci, Changsha, Hunan, Peoples R China.;[Lin, Qian] Chinese Acad Agr Sci, Inst Bast Fiber Crops, Changsha, Hunan, Peoples R China.
通讯机构:
[Li, Fengna] C;Chinese Acad Sci, Inst Subtrop Agr, Subtrop Reg, Changsha, Hunan, Peoples R China.
关键词:
antioxidative;fatty acids;finishing pig;growth performance;ramie
摘要:
This study was conducted to evaluate the effects of ramie (Boehmeria nivea, previously known as a fibre crop and also called “China grass”) included in diets on growth performance, antioxidative capacity and muscular fatty acid profile of finishing pigs. A total of 180 Xiangcun Black pigs (initial body weight =70.71±1.21kg) were randomly allotted to 1 of 5 dietary treatments with six pens of six pigs per pen. The pigs were provided a basal diet or a diet contained 3%, 6%, 9% or 12% of ramie powder during a 50-day experiment period. The results showed that the inclusion of ramie increased (quadratic, p<0.05) the average daily gain (ADG) and gain:feed ratio (G:F) with the highest value of ADG and G:F in 3% ramie group, but ramie content in the diet up to 9% reduced the growth performance of the pigs compared with that of 3% ramie group. The activity of serum total superoxide dismutase (SOD) was increased (linear, p<0.05) by ramie, while content of malondialdehyde was decreased (linear, p<0.05). As increasing the dietary ramie level, the mRNA expression level of SOD1 was increased quadratically (p<0.05) in muscle tissues. Moreover, the addition of ramie linearly increased (p<0.05) polyunsaturated fatty acids content, whereas it linearly reduced (p<0.05) the lipid indices of atherogenicity (AI) and thrombogenicity (TI) in muscle tissues, and lower values of AI and TI reflect a “healthier” fat composition. The results indicated that ramie in a diet not more than 9% may improve antioxidative capacity with no detrimental impact on growth performance of Chinese native finishing pigs; meanwhile, it could beneficially change the pork fatty acid pattern which has a positive impact on consumer's health. © 2018 Blackwell Verlag GmbH
语种:
英文
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Oral Administration of Lactobacillus delbrueckii during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model
作者:
Li, Yinghui;Hou, Shuling;Peng, Wei;Lin, Qian;Chen, Fengming;...
期刊:
Oxidative Medicine and Cellular Longevity ,2019年2019:6919803 ISSN:1942-0900
通讯作者:
Huang, Xingguo
作者机构:
[Li, Yinghui; Yang, Lingyuan; Chen, Fengming; Huang, Xingguo; Peng, Wei; Hou, Shuling] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.;[Li, Yinghui; Yang, Lingyuan; Chen, Fengming; Huang, Xingguo; Peng, Wei; Hou, Shuling] CICAPS, Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China.;[Li, Yinghui; Yang, Lingyuan; Chen, Fengming; Huang, Xingguo; Peng, Wei; Hou, Shuling] Engn Res Ctr Feed Safety & Efficient Utilizat Edu, Changsha 410128, Hunan, Peoples R China.;[Lin, Qian] Chinese Acad Agr Sci, Inst Bast Fiber Crops, Changsha 410205, Hunan, Peoples R China.;[Li, Fengna] Chinese Acad Sci, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg, Changsha 410125, Hunan, Peoples R China.
通讯机构:
[Huang, Xingguo] H;[Huang, Xingguo] C;[Huang, Xingguo] E;Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.;CICAPS, Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China.
关键词:
Antioxidants;Body fluids;Immune system;Nitric oxide;Peptides;Probiotics;Anti-oxidant activities;Antioxidant capacity;Glutathione peroxidase;Inducible nitric oxide synthase;Inflammatory cytokines;Lactobacillus delbrueckii;Protein expressions;System functionality;Laboratories;8 hydroxydeoxyguanosine;antioxidant;biological marker;catalase;cyclooxygenase 2;fractalkine;glutathione peroxidase;hydrocortisone;inducible nitric oxide synthase;interleukin 12;interleukin 1beta;interleukin 6;macrophage inflammatory protein 3alpha;malonaldehyde;noradrenalin;probiotic agent;secretory immunoglobulin;stress hormone;animal experiment;antioxidant activity;Article;bacterial colonization;blood level;comparative study;controlled study;enzyme activity;hydrocortisone blood level;immune response;intestine mucosa;Lactobacillus delbrueckii;newborn;nonhuman;noradrenalin blood level;piglet;protein expression level;suckling animal;weaning;animal;animal model;drug effect;female;Lactobacillus delbrueckii;oral drug administration;pathogenicity;pig;weaning;Antioxidants;Capacity;Concentration;Laboratories;Management;Peptides;Phases;Administration, Oral;Animals;Female;Intestinal Mucosa;Lactobacillus delbrueckii;Models, Animal;Swine;Weaning
摘要:
Early colonization in the gut by probiotics influences the progressive development and maturity of antioxidant and immune system functionality in the future. This study investigated the impact of orally administrated Lactobacillus delbrueckii (LAB) during the suckling phase on future antioxidant and immune responses of the host, using a piglet model. One hundred neonatal piglets received saline (CON) or LAB at the amounts of 1, 2, 3, and 4 mL at 1, 3, 7, and 14 d of age, respectively. The piglets were weaned at the age of 21 d and fed until the age of 49 d. Serum, liver, and intestinal samples were obtained at 21, 28, and 49 d of age. The results showed that LAB tended to decrease serum 8-hydroxy-2-deoxyguanosine concentration and decreased the concentration of serum and hepatic malondialdehyde, but increased the activity of hepatic glutathione peroxidase on days 21, 28, and 49. The concentrations of secretory immunoglobulin A and some inflammatory cytokines and chemokines were increased (P<0.05) in the intestinal mucosa of LAB-treated piglets on days 21, 28, and 49 compared to that of CON piglets. Likewise, protein expression of cyclooxygenase 2 and inducible nitric oxide synthase in the intestine of LAB-treated piglets was increased (P<0.05) during the whole period. These results indicate that administration of LAB to the suckling piglet could improve antioxidant capacity and stimulate intestinal immune response, and these long-lasting effects are also observed up to 4 weeks after weaning. A proper utilization of LAB to neonates would be beneficial to human and animal's future health. © 2019 Yinghui Li et al.
语种:
英文
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绿原酸的生物学功能及在养殖业中应用研究
作者:
韦良开;李瑞;陈凤鸣;文伟;黄兴国
期刊:
饲料工业 ,2019年40(1):22-26 ISSN:1001-991X
作者机构:
[黄兴国; 文伟; 李瑞; 韦良开; 陈凤鸣] 湖南农业大学动物科学技术学院,湖南长沙410128;[黄兴国; 文伟; 李瑞; 韦良开; 陈凤鸣] 湖南省畜禽安全生产协同创新中心,湖南长沙410128
关键词:
绿原酸;代谢;生物学功能;应用研究;多酚类
摘要:
绿原酸是一种广泛存在植物中的多酚类次生代谢产物,具有抗菌、消炎、抗氧化等作用,在畜禽养殖业中具有广泛的应用前景。文章主要从绿原酸的生物学功能及其在养殖业中的应用研究进行综述。
语种:
中文
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桑叶的营养价值及其在家禽生产中的应用
作者:
蔡巧利;韦良开;黄兴国;孔祥峰
期刊:
中国家禽 ,2019年(8):44-48 ISSN:1004-6364
作者机构:
湖南农业大学动物科学技术学院湖南畜禽安全生产协同创新中心;[孔祥峰] 中国科学院亚热带农业生态研究所;[黄兴国; 蔡巧利; 韦良开] 湖南农业大学
关键词:
桑叶;营养价值;家禽
摘要:
桑叶含有丰富的营养成分和特有的天然活性物质,是一种开发前景广阔的饲料资源。桑叶营养价值高、适口性良好,应用于家禽生产可以改善家禽健康、提高产品质量,同时,降低饲养成本、减少环境污染。文章综述了桑叶的营养价值及其在家禽生产中的应用现状,以期为桑叶的开发利用和在家禽生产的推广和普及提供参考。
语种:
中文
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霉菌毒素介导的氧化应激研究进展
作者:
陈凤鸣;陈佳亿;李颖慧;黄兴国
期刊:
动物营养学报 ,2019年31(9):3944-3952 ISSN:1006-267X
作者机构:
湖南农业大学动物科学技术学院,长沙,410128;[黄兴国; 李颖慧; 陈佳亿; 陈凤鸣] 湖南农业大学
关键词:
霉菌毒素;氧化应激;黄曲霉毒素;玉米赤霉烯酮;单端孢霉烯族毒素;赭曲霉毒素
摘要:
霉菌毒素是霉菌生长产生的次级代谢物,其高毒性和强致癌性严重威胁动物生产性能和人类健康,给畜牧业和食品工业带来巨大经济损失,因此,研究霉菌毒素的毒性机制具有重要的意义。霉菌毒素引起机体氧化应激,继而引发细胞毒性作用,如细胞凋亡、DNA损伤等。本文综述了主要的几种霉菌毒素吸收与代谢,重点阐述了由氧化应激介导的毒性作用,以期对霉菌毒素毒性机制有更加全面认识,为从缓解氧化应激的角度解决畜禽生产中霉菌毒素问题提供理论依据。
语种:
中文
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微藻的营养特性及其在畜牧业中应用的研究进展
作者:
韦良开;李瑞;陈凤鸣;黄兴国
期刊:
动物营养学报 ,2019年31(3):1044-1052 ISSN:1006-267X
作者机构:
湖南农业大学动物科学技术学院;[黄兴国; 李瑞; 韦良开; 陈凤鸣] 湖南畜禽安全生产协同创新中心
关键词:
微藻;生长;免疫;产品品质;畜牧业
摘要:
微藻是一种分布广泛且营养物质含量高、光合能力强的自养植物。微藻能合成多种拥有特殊生物活性的化合物,还能提高动物的生长性能、增强机体免疫机能、改善畜产品品质、解决畜牧业的环境污染问题,同时还可减轻食品与饲料以及燃料工业之间的竞争。因此,本文就微藻的营养特性及其对畜禽生长、免疫、产品品质等的影响进行综述,为微藻在畜牧业中的开发和利用提供参考。
语种:
中文
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Reduced dietary nitrogen with a high Lys:CP ratio restricted dietary N excretion without negatively affecting weaned piglets
作者:
Liu, Hongnan;Wu, Li;Han, Hui;Li, Yuying;Wang, Lijian;...
期刊:
动物营养(英文) ,2019年5(2):115-123 ISSN:2405-6545
通讯作者:
Li, Tiejun;Huang, Xingguo;Yao, Jiming
作者机构:
[Bai, Miaomiao; Liu, Hongnan; Wang, Lijian; Li, Tiejun; Han, Hui; Yin, Jie; Li, Yuying; Wu, Li] Chinese Acad Sci, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Key Lab Agroecol Proc Subtrop Reg,Inst Subtrop Ag, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Changsha 410125, Hunan, Peoples R China.;[Huang, Xingguo; Li, Tiejun; Liu, Hongnan] Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China.;[Wang, Lijian; Li, Tiejun; Yin, Jie; Li, Yuying; Wu, Li] Univ Chinese Acad Sci, Beijing 100039, Peoples R China.;[Huang, Xingguo; Li, Tiejun; Han, Hui] Hunan Agr Univ, Dept Anim Sci, Changsha 410128, Hunan, Peoples R China.;[Yao, JM; Li, Tiejun; Yao, Jiming; Fan, Wenjun] Guangdong Wangda Grp Co Ltd, Guangdong Wangda Grp Academician Workstn Clean Fe, Guangzhou 510663, Guangdong, Peoples R China.
通讯机构:
[Li, Tiejun] C;[Huang, XG; Li, TJ] H;[Li, Tiejun] U;[Yao, JM; Li, TJ] G;Chinese Acad Sci, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Key Lab Agroecol Proc Subtrop Reg,Inst Subtrop Ag, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Changsha 410125, Hunan, Peoples R China.
关键词:
Digestion;Feeding;Genetic mapping;Lysine;Nutrition;Protein
摘要:
We hypothesized that balancing the content of exogenous amino acids, especially lysine, to reduce protein content in swine diets could reduce nitrogen (N) pollution associated with animal husbandry. Two experiments (45 d each experiment) were performed on weaned piglets (Duroc x Landrace x Yorkshire, 28 d of age) to test this and to determine the optimal lysine to crude protein (Lys:CP) ratio in diet. In Exp. 1, 12 piglets (6 replicates [n = 6]) were fed diets containing different levels of CP (17% and 20%) but the same level of Lys. Increased CP content resulted in significant increases (P < 0.05) of average daily gain (ADG), average daily feed intake (ADFI), and body weight (BW), but did not affect the feed to gain ratio. In Exp. 2, 24 piglets (8 replicates [n = 8]) were fed 1 of 3 diets as follows: 1) 20% CP with a regular Lys:CP ratio (6.23%, control); 2) 17% CP with a reduced Lys:CP ratio (6.14%, LL); or 3) 17% CP with a standard Lys:CP ratio (7.32%, SL). The ADG, final BW, serum concentrations of growth hormone and insulin-like growth factor-1, villus height in the jejunum, and villus height to crypt depth ratio were the lowest in piglets fed LL diet, whereas blood urea N concentration was the lowest and the value of lipase activity was the highest in the piglets fed SL diet. The SL diet did not affect growth performance, intestinal morphology, or serum hormone concentrations, indicating that reduced dietary N with a high Lys:CP ratio can efficiently reduce dietary N excretion without negatively affecting weaned piglets.
语种:
英文
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德氏乳杆菌的生物学功能及其在动物生产中的应用
作者:
文伟;杨泰;韦良开;黄兴国
期刊:
动物营养学报 ,2019年31(4):1533-1539 ISSN:1006-267X
作者机构:
湖南农业大学动物科学技术学院,长沙,410128;[黄兴国] 湖南农业大学动物科学技术学院,长沙 410128;[黄兴国] 湖南省畜禽安全生产协同创新中心,长沙 410128;[文伟; 韦良开; 杨泰] 湖南农业大学
关键词:
德氏乳杆菌;生物学功能;免疫;抗氧化
摘要:
德氏乳杆菌在维持畜禽肠道健康、促生长和改善肉品质等方面具有重要作用。本文从肠道微生态、机体免疫、抗氧化及脂代谢等方面综述了德氏乳杆菌在动物生产中的应用效果及相关机制。
语种:
中文
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二甲基砜的生物学功能及其在畜禽生产中的应用前景
作者:
文伟;陈凤鸣;郭思杰;黄兴国
期刊:
动物营养学报 ,2019年31(7):3031-3038 ISSN:1006-267X
作者机构:
[黄兴国; 文伟; 陈凤鸣] 湖南农业大学动物科学技术学院,长沙410128;[黄兴国; 文伟; 陈凤鸣] 湖南省畜禽安全生产协同创新中心,长沙410128;湖南农业大学动物医学院,长沙410128;[郭思杰] 湖南农业大学
关键词:
二甲基砜;抗氧化;抗炎;应用前景
摘要:
二甲基砜是一种天然存在于自然界中的含硫有机化合物,具有抗炎、抗氧化、抗癌、预防疾病、增强机体免疫力等作用,被广泛用于保健功能和医疗用途,对于维持人和动物机体的健康发挥着重要作用,在动物的健康养殖中具有广阔的应用前景。本文综述了二甲基砜的理化性质、吸收与代谢以及生物学功能与相关机制,以期为其在动物生产中的应用提供参考依据。
语种:
中文
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德氏乳杆菌和低聚木糖对环江香猪生长性能和血浆生化参数的影响
作者:
蔡巧利;唐武;蒋慧姣;黄攀;玉中班;...
期刊:
动物营养学报 ,2019年31(8):3891-3897 ISSN:1006-267X
作者机构:
[黄兴国] 湖南农业大学动物科学技术学院,湖南省畜禽安全生产协同创新中心,长沙 410128;中国科学院亚热带农业生态研究所,动物营养生理与代谢过程湖南省重点实验室,长沙 410125;环江毛南族自治县水产畜牧兽医局,环江,547100;[蔡巧利; 孔祥峰; 蒋慧姣] 湖南农业大学;[唐武; 黄攀] 中国科学院亚热带农业生态研究所
关键词:
德氏乳杆菌;低聚木糖;环江香猪;生长性能;血浆生化参数
摘要:
本试验旨在研究德氏乳杆菌和低聚木糖对环江香猪生长性能和血浆生化参数的影响.选取平均体重为9.5 kg左右的环江香猪96头,随机分为3组,每组8个重复,每个重复4头(公母各占1/2) .对照组猪只饲喂基础饲粮,试验1组、试验2组猪只分别饲喂在基础饲粮中添加0.05%德氏乳杆菌、0.05%德氏乳杆菌+0.02%低聚木糖的试验饲粮.预试期3 d,正试期84 d.试验期间,每日记录采食量,分别于试验第1、28、56和84天称取空腹体重,计算各阶段平均日采食量( ADFI) 、平均日增重( ADG)和料重比( F/G) ;分别于试验第28、56和84天采集血液样品,检测血浆生化参数.结果表明:与对照组相比,试验第29~56天试验1组、试验2组的ADG显著升高( P<0.05) ,试验第57~84天试验1组F/G显著降低( P<0.05) ,试验第1~84天试验1组和试验2组F/G显著降低( P<0.05) .与对照组相比,试验第28天,试验1组血浆甘油三酯( TG)和总蛋白( TP)浓度以及试验2组血浆TP、白蛋白( ALB)和TG浓度与碱性磷酸酶( ALP)活性显著升高( P<0.05) ;试验第56天,试验1组血浆氨( NH3 )浓度和淀粉酶( AMS)活性以及试验2组血浆AMS活性显著升高( P<0.05) ;试验第84天,试验1组血浆葡萄糖( GLU)和TG浓度以及AMS和乳酸脱氢酶( LDH)活性显著降低( P<0.05) ,试验2组血浆TP浓度显著升高( P<0.05)且血浆谷草转氨酶( AST)和LDH活性显著降低( P<0.05) .另外,试验第56天,试验2组血浆TP、ALB、尿素氮( UN) 、GLU、TG、胆固醇( CHO)和低密度脂蛋白胆固醇( LDL?C)浓度以及肝脂酶( HL)活性显著高于对照组和试验1组( P<0.05) ,同时血浆AST和LDH活性显著低于对照组和试验1组( P<0.05) .上述结果提示,饲粮中单独添加德氏乳杆菌或同时添加德氏乳杆菌和低聚木糖可提高环江香猪的ADG、降低F/G,这可能与德氏乳杆菌和低聚木糖影响了机体氮代谢和糖脂代谢相关生化参数有关.
语种:
中文
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Dietary xylo-oligosaccharide supplementation alters gut microbial composition and activity in pigs according to age and dose
作者:
Pan, Jie;Yin, Jie;Zhang, Kai;Xie, Peifeng;Ding, Hao;...
期刊:
AMB EXPRESS ,2019年9(1):1-10 ISSN:2191-0855
通讯作者:
Huang, Xingguo;Kong, Xiangfeng
作者机构:
[Xie, Peifeng; Ding, Hao; Kong, Xiangfeng; Huang, Xingguo; Kong, XF; Pan, Jie] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.;[Xie, Peifeng; Ding, Hao; Yin, Jie; Kong, Xiangfeng; Pan, Jie; Zhang, Kai] Chinese Acad Sci, Key Lab Agroecol Proc Subtrop Reg,Inst Subtrop Ag, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Changsha 410125, Hunan, Peoples R China.;[Blachier, Francois] Univ Paris Saclay, Nutr Physiol & Ingest Behav, UMR INRA 914, AgroParisTech, Paris, France.;[Huang, Xingguo] Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Huang, XG; Kong, XF; Huang, Xingguo] H;[Kong, Xiangfeng] C;Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.;Chinese Acad Sci, Key Lab Agroecol Proc Subtrop Reg,Inst Subtrop Ag, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Natl Engn Lab Pollut Control & Waste Utilizat Liv, Changsha 410125, Hunan, Peoples R China.;Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China.
关键词:
Growing and fattening period;Gut microbiota;Bacterial metabolites;Pigs;Feed antibiotics
摘要:
This study explored the effect of dietary xylo-oligosaccharide (XOS) supplementation on the gut microbial composition and activity in pigs of different ages. Eighty pigs with an average body weight (BW) of 30kg were randomly divided into eight groups: A control group, a group that received antibiotic treatment, and six groups fed diets supplemented with 100, 250, and 500g/t XOS, of which three groups were in the growing period (GP, 30–65kg BW) and three groups in the growing and fattening period (GFP, 30–100kg BW). At the end of the experiment, the intestinal contents were sampled for analyses of gut microbiota and bacterial metabolites including short-chain fatty acids (SCFAs) and bioamines. The results showed that 100g/t XOS supplementation during the GFP significantly reduced the relative abundances of presumably pathogenic bacteria (Proteobacteria and Citrobacter), but enhanced the relative abundances of likely beneficial bacteria (Firmicutes and Lactobacillus). However, XOS supplementation during the GP showed little effect on the gut microbiota when pigs were killed at 100kg BW. Meanwhile, 100g/t XOS supplementation during the GFP decreased the level of 1,7-heptane diamine and increased the acetic acid, straight-chain fatty acids, and total SCFAs concentrations in the intestinal contents. Statistical analysis showed that both the dose and exposure time to XOS supplementation affected the microbial communities. In summary, 100g/t XOS supplementation during the GFP modified the gut microbiota composition and metabolic activity. Possible consequences of such changes for the host are discussed. © 2019, The Author(s).
语种:
英文
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Oral administration of Lactobacillus delbrueckii during the suckling period improves intestinal integrity after weaning in piglets
作者:
Li, Yinghui;Hou, Shuling;Chen, Jiashun;Peng, Wei;Wen, Wei;...
期刊:
Journal of Functional Foods ,2019年63:103591 ISSN:1756-4646
通讯作者:
Huang, Xingguo
作者机构:
[Huang, Xingguo] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.;CICAPS, Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Huang, Xingguo] H;Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China.
关键词:
Barrier function;Immune response;Intestinal morphology;Piglet;Probiotics
摘要:
This study was conducted to explore the effect of administrated Lactobacillus delbrueckii (LAB) during the suckling period on future intestinal integrity of the host, using a piglet model. Probiotic LAB increased final body weight, concentrations of immunoglobulin G and anti-inflammatory cytokines, but reduced diarrhea incidence by over 50% during any phase of experimental period. The intestinal villus height of the LAB-treated piglets were greater than that in the control piglets. Along with lower activity of serum diamine oxidase in the LAB piglets, there was a concurrent increase in mRNA expression of intestinal tight junctions proteins. We conclude that LAB, given to suckling piglets, stimulates immune response and improves intestinal morphology and barrier function, thereby mitigating diarrhea and promoting growth, importantly, these beneficial effects could be maintained up to 4 weeks after weaning. A proper utilization of LAB to neonates would be beneficial to future intestinal health. © 2019 The Authors
语种:
英文
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